Your Drugs and Devices are Rarely Simple

In Vivo Assays (conscious, telemetered, anesthetized) are utilized because, in vivo, different physiological states, metabolites, autonomic baroreceptor function, and vascular responses can modulate the effects and liabilities of a test article or device.

Quality repeat sampling focused on all important cardiac parameters

• Integrity of autonomic nervous system and metabolism
• No obfuscation by anesthetics
• Measures vascular and cardiac parameters and baroreceptor function
• Evaluates inotropy, lusitropy, and vascular properties
• Studies reperfusion arrhythmias
• Intra-coronary dosing